Hidradenitis suppurativa (HS) is a chronic skin condition that causes painful bumps underneath the skin, most commonly in the underarms and groin areas. These bumps can become infected and form pus filled pockets underneath the skin.
2. What causes hidradenitis suppurativa?
While the exact cause is unknown, hidradenitis suppurativa is believed to be caused by blocked hair follicles. Another factor could be family history of the condition.
3. How is hidradenitis suppurativa diagnosed?
Your doctor will examine your skin. He/she will make the diagnosis based on the location, number, and types of bumps and pockets.
4. What are the signs and symptoms of hidradenitis suppurativa?
HS causes painful bumps (also known as "boils") underneath the skin. The bumps can first resemble pimples but are usually larger and appear most commonly in the underarms, groin and buttock areas, though they can be found elsewhere as well. These bumps are often painful. In addition, they can form pus filled pockets underneath the skin (also known as "abscesses"). These pockets or tunnels (also known as "fistulas") break from time to time and let out pus, giving off an unpleasant smell
The first sign of HS could be a painful bump that becomes inflamed, most commonly in the armpit or groin areas. Signs and symptoms typically begin to appear after puberty or in a person’s teens or twenties. HS is often associated with other inflammatory diseases.
The recurrent bumps from HS can cause extreme pain and discomfort. The impact that HS has on quality of life sometimes leads to insecurity, social seclusion, anxiety, and depression.
5. What is the purpose of this study?
This study is designed to assess the effects of the study drugs, compared to placebo, in men and women with moderate to severe HS after 16 weeks of dosing.